CPAP vs. Mandibular Advancement Device for Obstructive Sleep Apnea

Usually comparative studies of oral appliance and continuous positive airway pressure (CPAP) to treat obstructive sleep apnea are small and with limitations.

Recently in a randomized crossover trial that involved 126 obstructive sleep apnea (OSA) patients, researchers compared CPAP with an adjustable mandibular advancement device that was adjusted to the most comfortable maximum limit.  Sleep apnea was shown in patients mild, moderate and severe and the study lasted one month.

The baseline apnea index (AHI) was 26 events per hour.  AHI was markedly decreased both in CPAP and oral device.  But mean on-treatment AHI was significantly lower with CPAP 5 vs. 11 events/hr, and the proportion of patients whose AHI normalized was higher with CPAP (about 75% vs. 40%).   The AHI difference between treatment groups of OSA and CPAP patients was striking between patients with severe OSA and moderate OSA.  Patient compliance was significantly higher with the mandibular device than with CPAP (average reported use 6.5% vs. 5.2 hours).

Blood pressure was measured for 24 hours and were unchanged in both groups.  Equally improved daytime sleepiness was seen in both groups.  When eight quality of life indicators were evaluated, the mandibular appliance was equal to CPAP in four indicators and superior to CPAP in four indicators.

Dental Sleep and TMD Center of Illinois, a premiere snoring and apnea treatment center in Naperville has been providing the CPAP alternative treatment of oral appliance therapy for over 15 years successfully. For more information on this physician recommended treatment option, visit www.TiredOfSnoring.com or call us at (630) 369-5508.

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